Fixed Combinations of Primrose root and Thyme

Published April 4, 1992.
List of German Commission E Monographs (Phytotherapy)

Composition of Drug

Fixed combinations consisting of:

Primrose root corresponding to B. Anz. 122, July 6, 1988;
Thyme corresponding to B. Anz. 228, December 5, 1984;

and their preparations in effective dosage.


Colds and disease of the upper respiratory tract with viscous phlegm.


None known.

Side Effects

Occasionally, gastric discomforts and nausea may occur.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

The individual components of the combination must each be present at 50 - 75 percent of the daily dosage given in the monographs for the individual herbs.

Mode of Administration

Comminuted drug and galenical preparations for oral intake.


An expectorant effect is documented for preparations of primrose root and thyme. In addition, thyme has antibacterial and bronchospasmolytic action. Primrose root has secretolytic action. Pharmacological tests for the effectiveness of fixed combinations are not available.