Fixed Combinations of Ginger root, Gentian root, and Wormwood

Published December 18, 1991.
List of German Commission E Monographs (Phytotherapy)

Name of Drug

Fixed combinations of ginger root, gentian root, and wormwood.

Composition of Drug

Fixed combinations consisting of:

Ginger root corresponding to B. Anz. 85, May 5, 1988;
Gentian root corresponding to B. Anz. 223, November 30, 1985;
Wormwood corresponding to B. Anz. 228, December 5, 1984;

and their preparations in effective dosage.


Loss of appetite, dyspeptic discomfort such as a sensation of fullness and flatulence.


Gastric and duodenal ulcers.

Side Effects

None known.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

The individual components must each be present at 30 - 50 percent of the daily dosage given in the monographs for the individual herbs.

Deviating dosages must be justified for the specific preparations (e.g., comparative bitter values).

Mode of Administration

Comminuted drug and bitter-tasting galenical preparations for oral intake.


For preparations of ginger root, gentian root, and wormwood, an appetite-stimulating effect with promotion of gastric secretion is documented. Pharmacological tests for the effectiveness of fixed combinations are not available.