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Fixed Combinations of Peppermint leaf and Fennel seed

Published August 13, 1991.
List of German Commission E Monographs (Phytotherapy)

Composition of Drug

Fixed combinations consisting of:

Peppermint leaf corresponding to November 11, 1985 (B. Anz. p. 14335);
Fennel seed corresponding to March 11, 1991 (B. Anz. p. 2742);
and their preparations in effective dosage.


Dyspeptic discomfort, especially with mild spasms in the gastrointestinal region, flatulence, and a sensation of fullness.


In case of gallbladder disease, only to be used after consultation with a physician or pharmacist.


Preparations other than teas and preparations with essential oil contents comparable to those of teas. Side Effects In individual cases, allergic reactions to the skin and respiratory tract.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

The individual components of the combination must be equivalent to 50 - 75 percent of the daily dosage given in the monographs for the individual herbs.

Mode of Administration

Comminuted drug for teas and other galenical preparations for oral use.

Duration of Application

Fennel preparations should not be used over extended time periods (several weeks) without consultation with a physician or pharmacist.


A spasmolytic and carminative effect is documented for peppermint leaf and fennel seed. Pharmacological tests for the effectiveness of fixed combinations are not available.