Fixed Combinations of Anise seed, Fennel seed and Caraway seed

Published August 13, 1991.
List of German Commission E Monographs (Phytotherapy)

Composition of Drug

Fixed combinations consisting of:

Anise seed corresponding to April 11, 1988 (B. Anz. p. 2943);
Fennel seed corresponding to March 11, 1991 (B. Anz. p. 2742);
Caraway seed corresponding to December 14, 1989 (B. Anz. 22a, February 1, 1990);

and their preparations in effective dosage.


Dyspeptic discomfort, especially with mild spasms of the gastrointestinal region, flatulence, and a sensation of fullness.


Oversensitivity to anise, fennel, or anethole.


Preparations other than teas and preparations with essential oil contents comparable to those of teas. Side Effects In individual cases, allergic reactions of the skin, respiratory tract, and gastrointestinal tract.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

The individual components of the combination must each be present at 30 - 55 percent of the amounts recommended as daily dosage in the monographs for the individual herbs.

Mode of Administration

Comminuted drug for teas and other galenical preparations for oral intake.

Duration of Use

Fennel preparations should not be taken over extended time periods (several weeks) without consultation with a physician or pharmacist.


A spasmolytic and antibacterial effect is documented for preparations of anise, fennel, and caraway. Pharmacological tests for the effectiveness of fixed combinations are not available.