Fixed Combinations of Valerian root and Hops

Published February 27, 1991.
List of German Commission E Monographs (Phytotherapy)

Name of Drug

Fixed combinations of valerian root and hops.

Composition of Drug

Fixed combinations consisting of:

Valerian root corresponding to the monograph published May 15, 1985;
Hops corresponding to the monograph published December 5, 1984;

as well as preparations in effective dosage.


Nervous sleeping disorders, conditions of unrest.

Side Effects

None known.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

The individual combination components must be at a concentration of 50 - 75 percent of the daily or single dosage given in the monograph for the single herb. Deviating dosages must be specifically justified for each preparation.

Mode of Administration

Comminuted drug for tea and other galenical preparations for oral applications.


A sedative and sleep-promoting action is documented for preparations of valerian and hops. Pharmacological experiments with this combination gave indication of a sedative and sleep-promoting action.