Published September 1, 1990.
List of German Commission E Monographs (Phytotherapy)
Uzarae radix, uzara root.
Uzara root consists of the dried, underground parts of 2- to 3- year-old plants of Xysmalobium undulatum (L.) R. Brown [Fam. Asclepiadaceae], as well as their preparations in effective dosage.
The drug contains glycosides with cardenolide structure.
Nonspecific, acute diarrhea.
Therapy with cardiac glycosides.
Unless otherwise prescribed:
Initial single dosage:
preparations equivalent to 1 g herb or 75 mg total glycosides. Daily dosage:
equivalent to 45 - 90 mg of total glycosides, calculated as uzarin. Mode of Administration Ethanol-water extracts in liquid form, or as dry extracts obtained from methanol-water extractions for internal use.
If diarrhea persists for more than 3 - 4 days, consult a physician.
Inhibits intestinal motility
In high dosage, digitalis-like effects on the heart.