Published July 27, 1990.
List of German Commission E Monographs (Phytotherapy)
Senecionis herba, senecio herb.
Senecio herb consists of the above-ground parts of Senecio nemorensis ssp. fuchsii C. Gmelin [Fam. Asteraceae], as well as preparations thereof.
Senecio herb is used for diabetes mellitus, hemorrhage, high blood pressure, for spasms, and as a uterine stimulant.
The effectiveness for diffuse mucosal hemorrhages is not sufficiently verified.
The effectiveness for the other claimed uses is not documented.
Senecio herb contains varying amounts of toxic pyrrolizidine alkaloids (PA) which are known to have organotoxic, in particular hepatotoxic, effects. Carcinogenic activity, operating through a genotoxic mechanism, has been demonstrated in animal experiments.
In addition to being an ineffective remedy for diabetes mellitus, use of the herb represents a considerable health risk.
The therapeutic administration of senecio herb is not justifiable because of its insufficient or undocumented effectiveness and the presence of toxic pyrrolizidine alkaloids.
Shortening of hemorrhage.