Published July 27, 1990.
List of German Commission E Monographs (Phytotherapy)
Petasitidis rhizoma, petasites root.
Petasites root consists of the dried underground parts of Petasites hybridus (L.) Ph. Gartn., B. Mey. et Scherb. [Fam. Asteraceae], as well as its preparations in effective dosage.
The drug contains sesquiterpenes such as petasin.
Petasites root also contains pyrrolizidine alkaloids with 1,2-unsaturated necine structure and their N-oxides.
Supportive therapy for acute spastic pain in the urinary tract, particularly if stones exist.
Unless otherwise prescribed:
Preparations equivalent to 4.5 - 7 g drug. The daily dose must not exceed 1 µg (mcg) of pyrrolizidine alkaloids with 1,2-necine structure, including their N-oxides.
Extracts obtained with ethanol or lipophilic solvents and other galenical preparations for internal use.
Not longer than 4 - 6 weeks per year.