Published July 27, 1990.
List of German Commission E Monographs (Phytotherapy)
Farfarae folium, coltsfoot leaf.
Coltsfoot leaf consists of the fresh or dried leaves of Tussilago farfara L. [Fam. Asteraceae], as well as its preparations in effective dosage.
The drug contains mucilage and tannins. Coltsfoot leaf also contains varying amounts of pyrrolizidine alkaloids with a 1,2-unsaturated necine structure and their N-oxides.
Acute catarrh of the respiratory tract with cough and hoarseness, acute, mild inflammation of the oral and pharyngeal mucosa.
Unless otherwise prescribed:
4.5 - 6 g of drug; equivalent preparations. The daily dosage of coltsfoot tea (drug) and of tea mixtures must not exceed 10 µg pyrrolizidine alkaloids with 1,2 unsaturated necine structure, including their N-oxides.
The daily dosage for extracts and pressed juice from fresh plants must not be more than 1 µg of total pyrrolizidine alkaloids with 1,2 unsaturated necine structure, including their N-oxides.
Comminuted drug for infusions, pressed plant juice or other galenical preparations for internal use.
Not longer than 4 - 6 weeks per year.
Unless otherwise stipulated:
Ointments or other preparations for external use are made up with 5 - 20 percent of the drug and prepared accordingly. The daily dose should not exceed more than 100 µg pyrrolizidine alkaloids with 1, 2-unsaturated necine structure including their N-oxides.
Furthers the formation of callus