Sweet Clover (Meliloti herba)

Published March 13, 1986; Revised March 13, 1990.
List of German Commission E Monographs (Phytotherapy)


Name of Drug

Meliloti herba, sweet clover, yellow melilot.

Composition of Drug

Sweet clover consists of the dried or fresh leaf and flowering branches of Melilotus officinalis (L.) Pallas and/or M. altissimus Thuillier [Fam. Fabaceae], as well as their preparations in effective dosage.

The herb contains 5,6-benzo-pyrone (coumarin).

Other ingredients are 3,4-dihydro coumarin (melilotin), o-coumaric acid, the glycoside melilotoside and flavonoids.



Problems arising from chronic venous insufficiency, such as pain and heaviness in legs, night cramps in the legs, itching, and swelling. For the supportive treatment of thrombophlebitis, post-thrombotic syndromes, hemorrhoids, and lymphatic congestion. External:

Contusions and superficial effusions of blood. Contraindications None known.

Side Effects

In rare cases headaches.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

Average daily dosage:

Herb or preparation in amounts corresponding to 3 - 30 mg coumarin; Parenteral application corresponding to 1 - 7.5 mg coumarin. The effective dosage for sweet clover preparations in fixed combinations must be documented for each specific preparation.

Mode of Administration

Comminuted herb for infusions and other galenical preparations for oral use.

Liquid forms of medication for parenteral application.

Ointments, liniments, cataplasms and herbal sachets for external use.

Ointments and suppositories for rectal use.


Anti-edematous for inflammatory and congestive edema by increase of venous reflux and improvement of lymphatic kinetics.

Animal experiments showed an increase in healing wounds.