Fixed Combinations of Anise seed, Linden flower, and Thyme

Published April 4, 1992.
List of German Commission E Monographs (Phytotherapy)

Composition of Drug

Fixed combinations consisting of:

Anise seed corresponding to B. Anz. 122, July 6, 1988;
Linden flower corresponding to B. Anz 164, September 1, 1990;
Thyme corresponding to B. Anz 228, December 5, 1984;

and their preparations in effective dosage.


Catarrhs of the upper respiratory tract with dry cough.


Oversensitivity to anise and anethole.

Side Effects

Occasionally, allergic reactions of skin, respiratory tract, and gastrointestinal tract.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

Linden flower must be present at the dosage given in the monograph. The other components of the combination must be present at 50 - 75 percent of the daily dosage given in the monographs for the individual herbs.

Mode of Administration

Comminuted drug for teas and other galenical preparations for oral intake.


An expectorant, antibacterial, and mild spasmolytic effect is documented for preparations of anise seed and thyme. A diaphoretic action is documented for linden flower. Pharmacological tests for the effectiveness of the fixed combinations are not available.