Published December 18, 1991; Revised September 3,1992.
List of German Commission E Monographs (Phytotherapy)
Fixed combinations of Javanese turmeric root, celandine herb, and wormwood.
Fixed combinations consisting of:
Javanese turmeric root corresponding to B. Anz. 122, July 6, 1988;
Celandine herb corresponding to B. Anz. 90, May 15, 1985;
Wormwood corresponding to B. Anz. 228, December 5, 1984;
and their preparations in effective dosage.
Spastic epigastric discomfort due to functional disorders of the biliary tract.
Obstruction of the biliary tract. If suffering from gallstones, to be used only after consultation with a physician or pharmacist.
Gastric discomfort may occur with extended use.
Unless otherwise prescribed:
Celandine herb must be present at the dosage given in the monograph. The other components of the combination must each be present at 30 - 50 percent of the daily dosage given in the monographs for the individual herbs.
Deviating dosages must be justified for the specific preparations (e.g., comparative bitter values).
Comminuted drug and galenical preparations thereof for oral intake.
For preparations of wormwood and Javanese turmeric root, a choleretic effect is documented; for celandine herb a papaverine-like, mildly spasmolytic effect on the gastrointestinal tract is known. Pharmacological tests for the effectiveness of fixed combinations are not available.