Fixed Combinations of Dandelion root with herb, Celandine herb, and Artichoke leaf (Fixed Combinations of Dandelion root with herb, Celandine herb, and Artichoke leaf)

Published December 18, 1991.
List of German Commission E Monographs (Phytotherapy)

Name of Drug

Fixed combinations of dandelion root with herb, celandine herb, and Artichoke leaf.

Composition of Drug

Fixed combinations consisting of:

Dandelion root with herb corresponding to B. Anz. 228 December 5, 1984;
Celandine herb corresponding to B. Anz. 90, May 15,1985;
Artichoke leaf corresponding B. Anz. 122, July 6, 1988;

and their preparations in effective dosage.


Spastic epigastric discomfort due to functional disorders of the biliary system.


Obstruction of the biliary tract, empyema of the gallbladder, ileus. Allergies to artichoke and other composites. In case of gallbladder diseases, to be used only after consultation with a physician or pharmacist

Side Effects

None known.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

Celandine must be present in the amount given in the monograph. The other two components of the combination must each be equivalent to 50-75 percent of the daily dosage indicated in the monographs for the individual herbs.

Mode of Administration

Comminuted drug and galenical preparations for oral intake.


A cholagogic effect has been documented for dandelion root with herb and artichoke leaf. Celandine herb has a papaverine-like, mildly spasmolytic effect on the upper gastrointestinal tract. Pharmacological tests for the effectiveness of combinations are not available.