Fixed Combinations of Peppermint oil and Fennel oil

Published August 13, 1991.
List of German Commission E Monographs (Phytotherapy)

Composition of Drug

Fixed combinations consisting of:

Peppermint oil corresponding to February 18, 1986 (B. Anz. p. 3077);
Fennel oil corresponding to March 11, 1991 (B. Anz. p. 2742);

and their preparations in effective dosage.


Dyspeptic discomfort, especially with mild spasms in the gastrointestinal region, flatulence, sensation of fullness.


In case of gallbladder disease, only to be used after consultation with a physician or pharmacist.

Not to be used by those suffering from obstruction of the biliary tract, cholecystitis, severe liver damage, pregnancy, or for infants and small children.

Side Effects

In individual cases, allergic reactions of the skin and respiratory tract. Sensitive individuals may experience gastric discomfort.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

The individual components of the combination must be equivalent to 50 - 75 percent of the daily dosage given in the monographs for individual herbs.

Mode of Administration

Essential oil and other galenical preparations thereof for oral use.

Duration of Application

Fennel oil should not be used over extended time periods (several weeks) without consultation with a physician or pharmacist.


Spasmolytic, carminative and antibacterial effects are documented for preparations of peppermint oil and fennel oil. Pharmacological tests for the effectiveness of fixed combinations are not available.