Fixed Combinations of Peppermint oil, Caraway oil, Fennel oil, and Chamomile flower

Published August 13, 1991.
List of German Commission E Monographs (Phytotherapy)

Composition of Drug

Fixed combinations consisting of:

Peppermint oil corresponding to February 18, 1986 (B. Anz. p. 3077);
Caraway oil corresponding to December 14, 1989 (B. Anz. 22a, February 1, 1990);
Fennel oil corresponding to March 11, 1991 (B. Anz. p. 2742);
Chamomile flower corresponding to November 1, 1984 (B. Anz. p. 13327); and their preparations in effective dosage.


Dyspeptic discomfort, especially with mild spasms in the gastrointestinal region, flatulence, sensation of fullness.


In case of gallbladder disease, only to be used after consultation with a physician or pharmacist.

Not to be used in case of biliary tract obstruction, cholecystitis, severe liver diseases, pregnancy, or for infants and small children.

Side Effects

In individual cases, allergic reactions of the skin and respiratory tract. Sensitive individuals may experience gastric discomfort.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

The individual components of the combination must be equivalent to 25 - 40 percent of the daily dosage given in the monographs for the individual herbs.

Mode of Administration

Essential oil, comminuted drug, and galenical preparations thereof for oral use.

Duration of Application

Fennel preparations should not be used over extended time periods (several weeks) without consultation with a physician or pharmacist.


Spasmolytic, carminative, and antibacterial effects are documented for peppermint oil, caraway oil, fennel oil, and chamomile flower. Pharmacological tests for the effectiveness of fixed combinations are not available.