Petasites root (Petasitidis rhizoma)

Published July 27, 1990.
List of German Commission E Monographs (Phytotherapy)

Pestwurzelstock

Name of Drug

Petasitidis rhizoma, petasites root.

Composition of Drug

Petasites root consists of the dried underground parts of Petasites hybridus (L.) Ph. Gartn., B. Mey. et Scherb. [Fam. Asteraceae], as well as its preparations in effective dosage.

The drug contains sesquiterpenes such as petasin.

Petasites root also contains pyrrolizidine alkaloids with 1,2-unsaturated necine structure and their N-oxides.

Uses

Supportive therapy for acute spastic pain in the urinary tract, particularly if stones exist.

Contraindications

Pregnancy, nursing.

Side Effects

None known.

Interactions with Other Drugs

None known.

Dosage

Unless otherwise prescribed:

Daily dosage:

Preparations equivalent to 4.5 - 7 g drug. The daily dose must not exceed 1 ¬Ķg (mcg) of pyrrolizidine alkaloids with 1,2-necine structure, including their N-oxides.

Mode of Administration

Extracts obtained with ethanol or lipophilic solvents and other galenical preparations for internal use.

Duration of Administration

Not longer than 4 - 6 weeks per year.

Action

Antispasmodic.