Celandine herb (Chelidonii herba)

Published May 15, 1985.
List of German Commission E Monographs (Phytotherapy)


Name of Drug

Chelidonii herba, celandine herb.

Composition of Drug

Celandine herb consists of the dried, above-ground parts of Chelidonium majus L. [Fam. Papaveraceae], gathered during flowering season, as well as its preparations in effective dosage.

The herb contains at least 0.6 percent total alkaloids, calculated as chelidonine and based on the dried herb.


Spastic discomfort of the bile ducts and gastrointestinal tract.


None known.

Side Effects

None known.

Interactions with Other Drugs

None known.


Unless otherwise prescribed:

Average daily dosage 2 - 5 g of herb, equivalent to 12 - 30 mg total alkaloids calculated as chelidonine. Mode of Administration Cut herb, herb powder or dried extracts for liquid and solid medicinal forms for internal use.


There is evidence of a mildly antispasmodic, papaverine-like action on the upper digestive tract.

In animal experiments:

cytostatic, nonspecific immune stimulation. Note: The blood pressure-lowering effects and the therapeutic effectiveness for mild forms of hypertonia (borderline hypertonia) need further investigation.